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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0a5e272ef5e9246824401b16e452b5313e232e31a583d575a7318c58be7de3' 
  AND token = 'P8raXoHMTE46UNez1Tyzm/JQz3ujXKb8aj8QTZJP2Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}