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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3c22a13ea17242b38ba2c8f480ead23394193f422aae4ce02245ca6fbee488a' 
  AND token = '8yIT0Nqlyq7CWXvKEejCYkvYaT+X3fl16RNtj9o27do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}