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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e234f5a14139c4acf309a85f795048703d0e726ef856ea7b8dccbc50fd0ecef6' 
  AND token = 'yxaT+IMaEWe0jH8xlBFSexW4hX6K21MUaH3L4Y7t4Cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}