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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccbfb2aeea9aba912867cbf48d2e1bed12646d7fb665380e0e5cabd4df4a4364' 
  AND token = '7UslrH1gaxI3X5MmfRTrbGHYuKTzjf0Mw8BAxI+qXq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}