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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1285e8748877077cc3b86dc7ec584474e088c50339d7b5635ed4b580ce5639' 
  AND token = 'm5/GtovhNOyKPe+HSBmi4UqVsnPn0jy9ZbWrnW2CELI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}