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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6f3d8730e13becdbfc0752cb233bb061f8454154174b1940599740501d9a6c' 
  AND token = '/xbix8UDLXMUHFYX5RcriZtqm1vsRbMsEgsFfoJWFd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}