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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1624f866f12071aa47f6178f113410a5d6a08ee57038bfa59ac1877163febf7' 
  AND token = 'XwbNQ/8pCyfcsu/vTPJTaacn5xArcDsCeXAEiz9ORB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}