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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed337f0f1b89a944aa3da8c0fb2434e65d32387c934a535241abe7757af9420c' 
  AND token = '+NeX/qU5aeLgsGTbassFdiUwrOm5tDs5F3sj8X/r8WU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}