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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f61e208caf7974fc55662e38767d24ad1d366e12540dc68420b9b3881dd2fe18' 
  AND token = 'VgWT1DdyO/cSRwsuS/Xgsr82i+2cmKk8Io5srvH8dko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}