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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac066c32005f703e65e8818deca66fb08a2c252c731b708ec01286ad3a03e06d' 
  AND token = '3+GEBB/dMS2aJMSE3/cAVz4LTOoEetoRHHvCVLZY0No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}