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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550801310eca9af66f1cefc97f0e69bb345e2b623e144d7c39698bfaa4638e80' 
  AND token = 'Wynx80GOsM44dTxHtJUhOgTXhp9P0DQ66LQD8m+Pfzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}