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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e8ff4f8cf46cc84471ab64e149e0812decd3c990785c28b0e8efe5815f5f9b' 
  AND token = 'Kge+ml/uEaXxcoRJkhuE8gRJhe7PZSPRpbCITAIY/gU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}