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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a44c052e4c76cd87c8638b87340619e8dd1bd8fe8e77c07b9cc0f82182c746a' 
  AND token = 'PXHyXVCUjEeYQAHCQObKy3PNO7kZ5b5vXuaQyMtUi24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}