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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e1fe6a07776a59b0e088c2f1e10108dbac289fc8cb3cc7530c9688e7410ed63' 
  AND token = 'Lktby9R2ODru98An73MNi6B54fqSP1g0bjUzMIapLbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}