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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d9b5b92f02531af3bb9413a0d68e4da4c2aff4a7a260a85e5808b6a0930616' 
  AND token = 'IHSqScVxMMssTw/65uhp1pkj7MpTAN3OxggnYlGyz/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}