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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b0ccc8897a3160287c66cf2b7d7ece99193772b264dae4e4c9e1b5719c8b61' 
  AND token = 'BPxzq5J3pz2t3mN3Rb5xIQGLzxO43F+1yRJgWgrsiAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}