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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f3a5107bffb068c190c6f47a62e2870aafdff2275d6f6ca99b43d77b8b9b1c' 
  AND token = '2VX9P0LxepAIL/y3ITm61T62TASH+MYCqoDA6JQyxOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}