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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33312e4a8abdd1028b3a27dd926c9fe8ce7c7be0c385506e745b294d3a2e7b2' 
  AND token = 'qi0LnlFFdob2X7K9XPzTfNwUFEw22wmoIew3zdEk8+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}