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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '373f4e56da3a838f0a99f9b7a7224f2cf26ab18bafbe371b1e709c7034516a29' 
  AND token = 'xitdU4sIOV5YErfz7jdEBr+5OEf4u1A1f2SkzJa8e2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}