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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4386428ffccf048c0bf1591c2afdc5c8a108093d9abc855cc8e4981e8dae918' 
  AND token = 'ZqhMW0ALZk3sB79qI2FVVeKwvAK0gLeb7+pcr+eJImo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}