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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7653609b1b3fbae1bd7635f88039ba54aa80bb5e800943e3cbdca802b56414' 
  AND token = 'XnRMFdbrHsJ/9g95s7T+hc0SeBYi967tG9dG+n/FWIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}