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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df58df0219a89242b73f9da6e23d61724c3b9e685e7a408b3e2830acfb3a125' 
  AND token = '4pMtWK8qrsfKHKSZhtcTlqOmkqNzzq/s+eFvhT5hqoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}