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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0492f33feb42679fb204723ac9d489cc5de7d20486b8424fe723d3b57019fb5' 
  AND token = '29lI6lTdcG+TC+nGNXEQFLyKpQydWm1+GNlw0iE0Djs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}