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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2482676a4204653627bb84e2581a10bd76dbc61dcde951b4289c85b87ab5eb' 
  AND token = '7bpRkGmLBHu6RPh4qmS+an87a95whdZLVoubIRuACqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}