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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec522d1ca8e80ab98608fe033e6aedb1f507341ec7b525682b3ee06d19b5b83' 
  AND token = 'Z7ew12OEQBQG3sLepEbgrO8xOIiLJVZiIyJvlK1OI8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}