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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd17e66fba016dac920f9283c5becb9264f4be59a4ba0aabd817f6f2a90de6437' 
  AND token = 'RxrZieuObItxD67G6pLxigPB2blNIqKP4ZvId7vIb88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}