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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9578277325d4537ca83a7b08772d8c57d0d2e53d172da2b200c3b967db7f250' 
  AND token = '4WK/V6Qd8fEfEQpStPSYVAmHCVz6S8aIbHi+rdGiPzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}