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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d3fcf26e37478009f994001aa34372f6249ceb4c0b3737982c106bce3ac8fa4' 
  AND token = 'hz/0n7R/yjwc6QrinrTGdLOVm7ZlwGrkrm3tds2rKR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}