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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372db5c819b13c0ea8bc14c704d351309292045995b6b384bab696f46f67f977' 
  AND token = 'hS8ONfIFt+ONVr1s2eAD6H92j6SEgoyyFo5xpZFH3AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}