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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e61435e3edf7bec4c513043619ab31afd35e7bb7aef73cf4245a35c6f3924d9' 
  AND token = 'SndjrUdHf2HtQGiEEYWWAxcYutBgW5aEPO5DJRDUyeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}