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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d75fed2c9a386b3bbff153f91bb14085b456e7522d47b2925bb5fa6545d20ee' 
  AND token = '4k9j3bBopVvkOV/KtON+MCy6gw7+P8okBDXg13rTciQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}