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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051acd3ce16ddcd161b8a800fb6b784ddeaa1b1840879e38338959c82d83d91b' 
  AND token = 'nU3c3oWddZ1nHnpLTmD4UafUmRRRf0IRZwRKBrbx6b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}