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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072cf91c06ec20c63773c63a1a84ffe086ab9cc2cd434379141d5b601be0c85c' 
  AND token = 'OSRwVfuPWtVJOx9c1wgYRYmic6/bsWXJUgDhw8wFNjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}