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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac8f0b79bfe279f6fd956d72485b90d99889d680bcbea24b54e16af4cf5a307a' 
  AND token = 'cnnHdRmGkrExnpWuS986vBIYrJDncs7uTXA6EPkxl8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}