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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72210423d5cc20e7c50024861c68d32c7781a696faa0b05ab2c7253a95c18faf' 
  AND token = 'bLvuhzvx83VV9qpQkpprsN49dHhWKEnVW86mHmWIrC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}