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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '124b77ac35c0799eaaa2555a033193d39594d7805185053a2d2ac61ded4b3b34' 
  AND token = 'KWB65MyT5s+W2a6+HxOK8Ub+ddiZlofRuLuOYEkTAAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}