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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80053179c58773aae79552b1a660fe9b452d5c10b1d5042d0c93311735dd67b4' 
  AND token = 'hTwx7NAGRntm082jk7sI11SYwr5EZ9F1kFsoZhh/HOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}