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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7e2d776c0abf0c6440f83c80858c67fb2177548c21f2edc227fac17810fb41' 
  AND token = 'RVIoWRV0wpXPe75GNk99xYfE7O+Zc98+b6QNR9z4iTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}