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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9f8298c6ef394a829fc37160bf445e8f6f7203deb47664f483f8b3a230aec1d' 
  AND token = 'QEHOJE898okGYSD87xglHf850P1/+98w+mQSBGiKhRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}