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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d4a941fde334346bbf38fb01890d4d8e35fd5516f0f57c7e47d717a999140e' 
  AND token = 'iuWE/CpyFYaE6uwEh1TP1cW1RTdmNGTLOzReF/KQUtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}