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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd87e0e0196bde8b3e207527e56a9353e51ab2dba8fd829fe4a6f19127b7943' 
  AND token = 'D/VgNI6MOn5ew/mAePUac/q2S9Rsv5Cf9vOGgD0R6KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}