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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd5a5370f65a3ab376bc93fda94cdddce819520f9b488bdce7400caead6e47b4' 
  AND token = 'aaOjZ6rEdybQQl7rj1K3/s3uSqYW+reGfAZ7rI9Vh2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}