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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51567840fca1cd7e2d0589e6d68ee91edc80d8b80dd64d012e4a02fb5668c39' 
  AND token = 'dxFllht9STDpBAI1D7G1fqwZaKZaWs4RH0DY5bKojM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}