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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca1704df3151c9a83c2a64f0953b12d0ff4d10d67b3016cca2b60bbdbd3126c' 
  AND token = 'dZATRa+FGuyh8L0z1SpW3jZLzuggWl2tHoFc1vu5TTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}