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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e86320c34501b8ef27167fae9fb2dce67ee4008c8ceb9dd2fa051df0a6c2d2' 
  AND token = 'JsNWAchh3z5aDddxCK39Jf3vHbPg9fhwX0Z/rAA4lbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}