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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42cb95e1709f6c69fde09b2bbcc00f16ce537dd9b5554058338abf4393d284b7' 
  AND token = 'fncJt5trdWI0CPT/PGg5AVQtsp4e0wTmaFkPTE6l48c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}