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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c742c7c3719e4556d4ae032daf2d9162194a351c0ba85dc8940dca9e722c07' 
  AND token = 'tPNSTsJ8sFrm2It31IqXe8qqhy2fTuBnz7R7X1hNRfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}