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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4304429ae1a3b03f2f2a5964f894ce0f1a29681a3c18d55ea40ed3f030340186' 
  AND token = '6VxeE87OzSVdOB/CZ9HCLrHLorRT7Xvz8ceJeclqOZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}