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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c9f88bea182e6222dd7910c1248dafe000314e5d4e5f56b01b55b2ba4e85d7' 
  AND token = 'Qk/WYuUMmzOBR80oGKIM30LbXQ2C9NyqKbb2wcMlipg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}