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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f37dc0e32f3249aafabced6010cd3f94c99a632711f4aa01c2806e76461ab3' 
  AND token = 'ioZ2BEaKNdHx70zqfRNDSygkZE+honhP84bO73dRX1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}